| Nicosia to Savona | 1,457.24 mi (2,345.21 km) |
| Nicosia to Scafati | 1,093.60 mi (1,759.98 km) |
| Nicosia to Scalea | 1,012.94 mi (1,630.16 km) |
| Nicosia to Scandiano | 1,360.63 mi (2,189.72 km) |
| Nicosia to Scandicci | 1,317.49 mi (2,120.29 km) |
| Nicosia to Schio | 1,360.39 mi (2,189.33 km) |
| Nicosia to Sciacca | 1,137.69 mi (1,830.94 km) |
| Nicosia to Scicli | 1,047.72 mi (1,686.15 km) |
| Nicosia to Scordia | 1,040.54 mi (1,674.58 km) |
| Nicosia to Scorze | 1,323.34 mi (2,129.72 km) |
| Nicosia to Sedico | 1,340.29 mi (2,156.99 km) |
| Nicosia to Sedriano | 1,460.98 mi (2,351.22 km) |
| Nicosia to Segni | 1,186.05 mi (1,908.76 km) |
| Nicosia to Segrate | 1,446.27 mi (2,327.54 km) |
| Nicosia to Selargius | 1,357.04 mi (2,183.95 km) |
