| Nicholasville to University Place (Washington) | 2,014.71 mi (3,242.36 km) |
| Nicholasville to Upland (California) | 1,858.19 mi (2,990.47 km) |
| Nicholasville to Upper Arlington (Ohio) | 168.09 mi (270.52 km) |
| Nicholasville to Upper Grand Lagoon (Florida) | 537.71 mi (865.37 km) |
| Nicholasville to Upper Montclair (New Jersey) | 589.65 mi (948.95 km) |
| Nicholasville to Urbana (Illinois) | 248.02 mi (399.14 km) |
| Nicholasville to Urbana (Maryland) | 402.37 mi (647.55 km) |
| Nicholasville to Urbana (Ohio) | 159.33 mi (256.42 km) |
| Nicholasville to Urbandale (Iowa) | 553.26 mi (890.38 km) |
| Nicholasville to Utica (New York) | 607.86 mi (978.26 km) |
| Nicholasville to Uvalde (Texas) | 1,059.09 mi (1,704.44 km) |
| Nicholasville to Vacaville (California) | 2,019.00 mi (3,249.26 km) |
| Nicholasville to Vadnais Heights (Minnesota) | 661.94 mi (1,065.29 km) |
| Nicholasville to Vail (Arizona) | 1,528.42 mi (2,459.76 km) |
| Nicholasville to Valdosta (Georgia) | 491.94 mi (791.70 km) |
