| Nicholasville to Superior (Colorado) | 1,113.51 mi (1,792.03 km) |
| Nicholasville to Superior (Wisconsin) | 718.62 mi (1,156.51 km) |
| Nicholasville to Surprise (Arizona) | 1,583.58 mi (2,548.53 km) |
| Nicholasville to Susanville (California) | 1,925.77 mi (3,099.22 km) |
| Nicholasville to Sussex (Wisconsin) | 409.96 mi (659.77 km) |
| Nicholasville to Suwanee (Georgia) | 266.76 mi (429.31 km) |
| Nicholasville to Swansea (Illinois) | 297.62 mi (478.98 km) |
| Nicholasville to Sweetwater (Florida) | 871.99 mi (1,403.33 km) |
| Nicholasville to Sweetwater (Texas) | 968.28 mi (1,558.29 km) |
| Nicholasville to Sycamore (Illinois) | 357.63 mi (575.55 km) |
| Nicholasville to Sylacauga (Alabama) | 339.23 mi (545.94 km) |
| Nicholasville to Sylvania (Ohio) | 267.79 mi (430.96 km) |
| Nicholasville to Syosset (New York) | 624.21 mi (1,004.58 km) |
| Nicholasville to Syracuse (New York) | 567.53 mi (913.36 km) |
| Nicholasville to Syracuse (Utah) | 1,476.79 mi (2,376.67 km) |
