| Nicholasville to Storm Lake (Iowa) | 648.77 mi (1,044.10 km) |
| Nicholasville to Storrs (Connecticut) | 706.29 mi (1,136.66 km) |
| Nicholasville to Stoughton (Wisconsin) | 425.20 mi (684.29 km) |
| Nicholasville to Stow (Ohio) | 281.75 mi (453.43 km) |
| Nicholasville to Streamwood (Illinois) | 343.46 mi (552.74 km) |
| Nicholasville to Streator (Illinois) | 318.62 mi (512.76 km) |
| Nicholasville to Streetsboro (Ohio) | 288.01 mi (463.51 km) |
| Nicholasville to Strongsville (Ohio) | 277.66 mi (446.85 km) |
| Nicholasville to Stuart (Florida) | 780.37 mi (1,255.89 km) |
| Nicholasville to Stuarts Draft (Virginia) | 301.44 mi (485.11 km) |
| Nicholasville to Sturgis (Michigan) | 273.80 mi (440.64 km) |
| Nicholasville to Suamico (Wisconsin) | 500.12 mi (804.86 km) |
| Nicholasville to Sudley (Virginia) | 388.06 mi (624.53 km) |
| Nicholasville to Suffern (New York) | 598.22 mi (962.75 km) |
| Nicholasville to Suffolk (Virginia) | 443.33 mi (713.48 km) |
