| Nicholasville to Silver Firs (Washington) | 2,000.51 mi (3,219.51 km) |
| Nicholasville to Silver Spring (Maryland) | 415.38 mi (668.49 km) |
| Nicholasville to Silver Springs Shores (Florida) | 623.99 mi (1,004.21 km) |
| Nicholasville to Silverdale (Washington) | 2,023.78 mi (3,256.96 km) |
| Nicholasville to Silverton (Oregon) | 2,019.11 mi (3,249.44 km) |
| Nicholasville to Simi Valley (California) | 1,914.39 mi (3,080.91 km) |
| Nicholasville to Simpsonville (South Carolina) | 253.49 mi (407.95 km) |
| Nicholasville to Sioux City (Iowa) | 699.58 mi (1,125.86 km) |
| Nicholasville to Sioux Falls (South Dakota) | 745.96 mi (1,200.51 km) |
| Nicholasville to Skokie (Illinois) | 332.01 mi (534.32 km) |
| Nicholasville to Sleepy Hollow (New York) | 611.15 mi (983.56 km) |
| Nicholasville to Slidell (Louisiana) | 603.84 mi (971.79 km) |
| Nicholasville to Smithfield (North Carolina) | 381.46 mi (613.90 km) |
| Nicholasville to Smithfield (Utah) | 1,464.73 mi (2,357.26 km) |
| Nicholasville to Smithville (Missouri) | 549.66 mi (884.59 km) |
