| Nicholasville to Seymour (Tennessee) | 145.89 mi (234.79 km) |
| Nicholasville to Shady Hills (Florida) | 665.73 mi (1,071.39 km) |
| Nicholasville to Shafter (California) | 1,915.25 mi (3,082.30 km) |
| Nicholasville to Shaker Heights (Ohio) | 295.00 mi (474.76 km) |
| Nicholasville to Shakopee (Minnesota) | 662.49 mi (1,066.17 km) |
| Nicholasville to Sharon (Pennsylvania) | 316.62 mi (509.54 km) |
| Nicholasville to Sharonville (Ohio) | 96.56 mi (155.39 km) |
| Nicholasville to Shasta Lake (California) | 2,015.63 mi (3,243.84 km) |
| Nicholasville to Shawnee (Kansas) | 559.23 mi (899.99 km) |
| Nicholasville to Shawnee (Oklahoma) | 708.90 mi (1,140.87 km) |
| Nicholasville to Sheboygan (Wisconsin) | 436.65 mi (702.72 km) |
| Nicholasville to Shelby (North Carolina) | 245.69 mi (395.39 km) |
| Nicholasville to Shelbyville (Indiana) | 131.09 mi (210.97 km) |
| Nicholasville to Shelbyville (Kentucky) | 42.14 mi (67.82 km) |
| Nicholasville to Shelbyville (Tennessee) | 195.48 mi (314.59 km) |
