| Nicholasville to Sanford (Maine) | 817.15 mi (1,315.07 km) |
| Nicholasville to Sanford (North Carolina) | 341.59 mi (549.74 km) |
| Nicholasville to Sanger (California) | 1,913.75 mi (3,079.88 km) |
| Nicholasville to Santa Ana (California) | 1,878.43 mi (3,023.04 km) |
| Nicholasville to Santa Barbara (California) | 1,963.89 mi (3,160.58 km) |
| Nicholasville to Santa Clara (California) | 2,033.07 mi (3,271.91 km) |
| Nicholasville to Santa Clara (Oregon) | 2,036.96 mi (3,278.17 km) |
| Nicholasville to Santa Clarita (California) | 1,897.51 mi (3,053.75 km) |
| Nicholasville to Santa Cruz (California) | 2,042.64 mi (3,287.31 km) |
| Nicholasville to Santa Fe (New Mexico) | 1,192.45 mi (1,919.07 km) |
| Nicholasville to Santa Fe (Texas) | 842.79 mi (1,356.34 km) |
| Nicholasville to Santa Fe Springs (California) | 1,884.03 mi (3,032.05 km) |
| Nicholasville to Santa Maria (California) | 1,993.03 mi (3,207.47 km) |
| Nicholasville to Santa Monica (California) | 1,904.90 mi (3,065.64 km) |
| Nicholasville to Santa Paula (California) | 1,929.79 mi (3,105.70 km) |
