| Nicholasville to Oswego (Illinois) | 329.69 mi (530.59 km) |
| Nicholasville to Oswego (New York) | 570.74 mi (918.51 km) |
| Nicholasville to Otsego (Minnesota) | 690.95 mi (1,111.98 km) |
| Nicholasville to Ottawa (Illinois) | 329.60 mi (530.45 km) |
| Nicholasville to Ottawa (Kansas) | 582.18 mi (936.93 km) |
| Nicholasville to Ottumwa (Iowa) | 471.12 mi (758.20 km) |
| Nicholasville to Overland (Missouri) | 319.47 mi (514.13 km) |
| Nicholasville to Overland Park (Kansas) | 552.09 mi (888.50 km) |
| Nicholasville to Overlea (Maryland) | 446.08 mi (717.90 km) |
| Nicholasville to Oviedo (Florida) | 666.97 mi (1,073.39 km) |
| Nicholasville to Owasso (Oklahoma) | 630.22 mi (1,014.25 km) |
| Nicholasville to Owatonna (Minnesota) | 622.02 mi (1,001.05 km) |
| Nicholasville to Owensboro (Kentucky) | 139.49 mi (224.49 km) |
| Nicholasville to Owings Mills (Maryland) | 432.36 mi (695.82 km) |
| Nicholasville to Owosso (Michigan) | 353.31 mi (568.60 km) |
