| Nicholasville to Orangevale (California) | 1,975.18 mi (3,178.74 km) |
| Nicholasville to Orchards (Washington) | 2,007.95 mi (3,231.49 km) |
| Nicholasville to Orcutt (California) | 1,993.16 mi (3,207.68 km) |
| Nicholasville to Oregon (Ohio) | 266.80 mi (429.38 km) |
| Nicholasville to Oregon (Wisconsin) | 430.39 mi (692.64 km) |
| Nicholasville to Oregon City (Oregon) | 2,010.28 mi (3,235.24 km) |
| Nicholasville to Orem (Utah) | 1,458.68 mi (2,347.51 km) |
| Nicholasville to Orinda (California) | 2,036.79 mi (3,277.90 km) |
| Nicholasville to Orland Park (Illinois) | 310.74 mi (500.08 km) |
| Nicholasville to Orlando (Florida) | 676.55 mi (1,088.79 km) |
| Nicholasville to Ormond Beach (Florida) | 626.12 mi (1,007.65 km) |
| Nicholasville to Oro Valley (Arizona) | 1,533.34 mi (2,467.68 km) |
| Nicholasville to Oroville (California) | 1,984.14 mi (3,193.16 km) |
| Nicholasville to Oshkosh (Wisconsin) | 472.04 mi (759.68 km) |
| Nicholasville to Oskaloosa (Iowa) | 489.63 mi (787.98 km) |
