| Newport News to Southern Pines (North Carolina) | 208.25 mi (335.14 km) |
| Newport News to Southfield (Michigan) | 515.27 mi (829.25 km) |
| Newport News to Southgate (Michigan) | 500.38 mi (805.28 km) |
| Newport News to Southlake (Texas) | 1,199.35 mi (1,930.17 km) |
| Newport News to Spanaway (Washington) | 2,414.46 mi (3,885.70 km) |
| Newport News to Spanish Fork (Utah) | 1,895.27 mi (3,050.15 km) |
| Newport News to Spanish Lake (Missouri) | 754.14 mi (1,213.67 km) |
| Newport News to Spanish Springs (Nevada) | 2,321.30 mi (3,735.77 km) |
| Newport News to Sparks (Nevada) | 2,324.72 mi (3,741.28 km) |
| Newport News to Spartanburg (South Carolina) | 336.92 mi (542.23 km) |
| Newport News to Spearfish (South Dakota) | 1,507.70 mi (2,426.41 km) |
| Newport News to Speedway (Indiana) | 557.93 mi (897.90 km) |
| Newport News to Spencer (Iowa) | 1,066.35 mi (1,716.13 km) |
| Newport News to Spokane (Washington) | 2,182.49 mi (3,512.38 km) |
| Newport News to Spokane Valley (Washington) | 2,173.26 mi (3,497.53 km) |
