| Newcastle under Lyme to University Place (Washington) | 4,675.71 mi (7,524.83 km) |
| Newcastle under Lyme to Upland (California) | 5,282.96 mi (8,502.10 km) |
| Newcastle under Lyme to Upper Arlington (Ohio) | 3,734.69 mi (6,010.40 km) |
| Newcastle under Lyme to Upper Grand Lagoon (Florida) | 4,325.32 mi (6,960.93 km) |
| Newcastle under Lyme to Upper Montclair (New Jersey) | 3,347.78 mi (5,387.73 km) |
| Newcastle under Lyme to Urbana (Illinois) | 3,927.40 mi (6,320.53 km) |
| Newcastle under Lyme to Urbana (Maryland) | 3,541.83 mi (5,700.02 km) |
| Newcastle under Lyme to Urbana (Ohio) | 3,757.36 mi (6,046.89 km) |
| Newcastle under Lyme to Urbandale (Iowa) | 4,060.37 mi (6,534.53 km) |
| Newcastle under Lyme to Utica (New York) | 3,289.45 mi (5,293.86 km) |
| Newcastle under Lyme to Uvalde (Texas) | 4,925.31 mi (7,926.52 km) |
| Newcastle under Lyme to Vacaville (California) | 5,170.37 mi (8,320.90 km) |
| Newcastle under Lyme to Vadnais Heights (Minnesota) | 3,869.76 mi (6,227.78 km) |
| Newcastle under Lyme to Vail (Arizona) | 5,169.14 mi (8,318.93 km) |
| Newcastle under Lyme to Valdosta (Georgia) | 4,191.41 mi (6,745.42 km) |
