| Newburyport to Southern Pines (North Carolina) | 696.56 mi (1,121.00 km) |
| Newburyport to Southfield (Michigan) | 628.68 mi (1,011.77 km) |
| Newburyport to Southgate (Michigan) | 628.24 mi (1,011.06 km) |
| Newburyport to Southlake (Texas) | 1,577.04 mi (2,537.99 km) |
| Newburyport to Spanaway (Washington) | 2,491.17 mi (4,009.14 km) |
| Newburyport to Spanish Fork (Utah) | 2,097.78 mi (3,376.06 km) |
| Newburyport to Spanish Lake (Missouri) | 1,045.41 mi (1,682.42 km) |
| Newburyport to Spanish Springs (Nevada) | 2,508.56 mi (4,037.14 km) |
| Newburyport to Sparks (Nevada) | 2,512.96 mi (4,044.23 km) |
| Newburyport to Spartanburg (South Carolina) | 803.69 mi (1,293.42 km) |
| Newburyport to Spearfish (South Dakota) | 1,639.06 mi (2,637.82 km) |
| Newburyport to Speedway (Indiana) | 822.80 mi (1,324.17 km) |
| Newburyport to Spencer (Iowa) | 1,222.50 mi (1,967.43 km) |
| Newburyport to Spokane (Washington) | 2,254.52 mi (3,628.29 km) |
| Newburyport to Spokane Valley (Washington) | 2,245.45 mi (3,613.69 km) |
