| New Port Richey East to St. George (Utah) | 1,886.77 mi (3,036.46 km) |
| New Port Richey East to St. Helens (Oregon) | 2,488.54 mi (4,004.91 km) |
| New Port Richey East to St. James (New York) | 1,025.35 mi (1,650.14 km) |
| New Port Richey East to St. John (Indiana) | 949.80 mi (1,528.56 km) |
| New Port Richey East to St. Joseph (Missouri) | 1,053.26 mi (1,695.05 km) |
| New Port Richey East to St. Louis (Missouri) | 837.96 mi (1,348.56 km) |
| New Port Richey East to St. Louis Park (Minnesota) | 1,293.42 mi (2,081.55 km) |
| New Port Richey East to St. Marys (Georgia) | 185.17 mi (298.00 km) |
| New Port Richey East to St. Marys (Pennsylvania) | 941.49 mi (1,515.17 km) |
| New Port Richey East to St. Matthews (Kentucky) | 710.74 mi (1,143.82 km) |
| New Port Richey East to St. Michael (Minnesota) | 1,316.58 mi (2,118.82 km) |
| New Port Richey East to St. Paul (Minnesota) | 1,286.93 mi (2,071.12 km) |
| New Port Richey East to St. Peter (Minnesota) | 1,272.60 mi (2,048.05 km) |
| New Port Richey East to St. Peters (Missouri) | 857.22 mi (1,379.56 km) |
| New Port Richey East to St. Petersburg (Florida) | 32.34 mi (52.04 km) |
