| New Port Richey East to Somersworth (New Hampshire) | 1,226.56 mi (1,973.96 km) |
| New Port Richey East to Somerton (Arizona) | 1,922.87 mi (3,094.56 km) |
| New Port Richey East to Somerville (Massachusetts) | 1,172.28 mi (1,886.60 km) |
| New Port Richey East to Somerville (New Jersey) | 966.20 mi (1,554.95 km) |
| New Port Richey East to Sonoma (California) | 2,379.13 mi (3,828.83 km) |
| New Port Richey East to Soquel (California) | 2,344.84 mi (3,773.66 km) |
| New Port Richey East to South Bend (Indiana) | 948.58 mi (1,526.60 km) |
| New Port Richey East to South Bradenton (Florida) | 55.64 mi (89.54 km) |
| New Port Richey East to South Burlington (Vermont) | 1,235.24 mi (1,987.93 km) |
| New Port Richey East to South Charleston (West Virginia) | 698.88 mi (1,124.73 km) |
| New Port Richey East to South Daytona (Florida) | 119.87 mi (192.91 km) |
| New Port Richey East to South El Monte (California) | 2,117.60 mi (3,407.95 km) |
| New Port Richey East to South Elgin (Illinois) | 999.80 mi (1,609.02 km) |
| New Port Richey East to South Euclid (Ohio) | 918.78 mi (1,478.64 km) |
| New Port Richey East to South Farmingdale (New York) | 1,007.57 mi (1,621.53 km) |
