| New Port Richey East to Smyrna (Delaware) | 863.37 mi (1,389.45 km) |
| New Port Richey East to Smyrna (Georgia) | 401.86 mi (646.73 km) |
| New Port Richey East to Smyrna (Tennessee) | 577.75 mi (929.80 km) |
| New Port Richey East to Snellville (Georgia) | 394.32 mi (634.60 km) |
| New Port Richey East to Snoqualmie (Washington) | 2,477.53 mi (3,987.20 km) |
| New Port Richey East to Snyder (Texas) | 1,125.85 mi (1,811.89 km) |
| New Port Richey East to Socastee (South Carolina) | 433.76 mi (698.07 km) |
| New Port Richey East to Socorro (Texas) | 1,427.18 mi (2,296.82 km) |
| New Port Richey East to Soddy-Daisy (Tennessee) | 504.85 mi (812.48 km) |
| New Port Richey East to Solana Beach (California) | 2,071.48 mi (3,333.73 km) |
| New Port Richey East to Soledad (California) | 2,309.27 mi (3,716.41 km) |
| New Port Richey East to Solon (Ohio) | 909.67 mi (1,463.97 km) |
| New Port Richey East to Somers Point (New Jersey) | 893.03 mi (1,437.19 km) |
| New Port Richey East to Somerset (Kentucky) | 619.68 mi (997.28 km) |
| New Port Richey East to Somerset (New Jersey) | 965.50 mi (1,553.83 km) |
