| New Port Richey East to Santa Rosa (California) | 2,393.37 mi (3,851.75 km) |
| New Port Richey East to Santaquin (Utah) | 1,839.48 mi (2,960.35 km) |
| New Port Richey East to Santee (California) | 2,055.74 mi (3,308.39 km) |
| New Port Richey East to Sapulpa (Oklahoma) | 948.21 mi (1,526.00 km) |
| New Port Richey East to Saraland (Alabama) | 370.85 mi (596.82 km) |
| New Port Richey East to Sarasota (Florida) | 64.35 mi (103.55 km) |
| New Port Richey East to Sarasota Springs (Florida) | 67.11 mi (108.00 km) |
| New Port Richey East to Saratoga (California) | 2,350.27 mi (3,782.39 km) |
| New Port Richey East to Saratoga Springs (New York) | 1,137.27 mi (1,830.26 km) |
| New Port Richey East to Saratoga Springs (Utah) | 1,853.30 mi (2,982.60 km) |
| New Port Richey East to Sartell (Minnesota) | 1,354.54 mi (2,179.92 km) |
| New Port Richey East to Satellite Beach (Florida) | 127.44 mi (205.09 km) |
| New Port Richey East to Sauk Rapids (Minnesota) | 1,351.63 mi (2,175.24 km) |
| New Port Richey East to Sault Ste. Marie (Michigan) | 1,262.26 mi (2,031.41 km) |
| New Port Richey East to Savage (Minnesota) | 1,281.83 mi (2,062.90 km) |
