| New Port Richey East to Sanford (Maine) | 1,239.90 mi (1,995.43 km) |
| New Port Richey East to Sanford (North Carolina) | 540.16 mi (869.31 km) |
| New Port Richey East to Sanger (California) | 2,211.56 mi (3,559.16 km) |
| New Port Richey East to Santa Ana (California) | 2,107.72 mi (3,392.04 km) |
| New Port Richey East to Santa Barbara (California) | 2,213.51 mi (3,562.30 km) |
| New Port Richey East to Santa Clara (California) | 2,347.51 mi (3,777.95 km) |
| New Port Richey East to Santa Clara (Oregon) | 2,474.87 mi (3,982.93 km) |
| New Port Richey East to Santa Clarita (California) | 2,143.76 mi (3,450.05 km) |
| New Port Richey East to Santa Cruz (California) | 2,349.52 mi (3,781.19 km) |
| New Port Richey East to Santa Fe (New Mexico) | 1,453.38 mi (2,338.99 km) |
| New Port Richey East to Santa Fe (Texas) | 754.71 mi (1,214.59 km) |
| New Port Richey East to Santa Fe Springs (California) | 2,118.27 mi (3,409.02 km) |
| New Port Richey East to Santa Maria (California) | 2,255.16 mi (3,629.32 km) |
| New Port Richey East to Santa Monica (California) | 2,142.34 mi (3,447.76 km) |
| New Port Richey East to Santa Paula (California) | 2,176.11 mi (3,502.12 km) |
