| New Port Richey East to Oswego (Illinois) | 980.34 mi (1,577.70 km) |
| New Port Richey East to Oswego (New York) | 1,104.57 mi (1,777.63 km) |
| New Port Richey East to Otsego (Minnesota) | 1,318.61 mi (2,122.10 km) |
| New Port Richey East to Ottawa (Illinois) | 968.68 mi (1,558.94 km) |
| New Port Richey East to Ottawa (Kansas) | 1,015.76 mi (1,634.71 km) |
| New Port Richey East to Ottumwa (Iowa) | 1,038.98 mi (1,672.08 km) |
| New Port Richey East to Overland (Missouri) | 845.15 mi (1,360.13 km) |
| New Port Richey East to Overland Park (Kansas) | 1,006.03 mi (1,619.04 km) |
| New Port Richey East to Overlea (Maryland) | 844.58 mi (1,359.21 km) |
| New Port Richey East to Oviedo (Florida) | 95.51 mi (153.70 km) |
| New Port Richey East to Owasso (Oklahoma) | 945.42 mi (1,521.51 km) |
| New Port Richey East to Owatonna (Minnesota) | 1,239.25 mi (1,994.38 km) |
| New Port Richey East to Owensboro (Kentucky) | 704.22 mi (1,133.33 km) |
| New Port Richey East to Owings Mills (Maryland) | 841.10 mi (1,353.62 km) |
| New Port Richey East to Owosso (Michigan) | 1,021.44 mi (1,643.85 km) |
