| New Port Richey East to Eugene (Oregon) | 2,473.17 mi (3,980.18 km) |
| New Port Richey East to Euless (Texas) | 911.88 mi (1,467.53 km) |
| New Port Richey East to Eureka (California) | 2,487.14 mi (4,002.67 km) |
| New Port Richey East to Eureka (Missouri) | 842.54 mi (1,355.94 km) |
| New Port Richey East to Eustis (Florida) | 74.14 mi (119.31 km) |
| New Port Richey East to Evans (Colorado) | 1,504.01 mi (2,420.47 km) |
| New Port Richey East to Evans (Georgia) | 367.78 mi (591.88 km) |
| New Port Richey East to Evanston (Illinois) | 993.04 mi (1,598.14 km) |
| New Port Richey East to Evanston (Wyoming) | 1,826.94 mi (2,940.17 km) |
| New Port Richey East to Evansville (Indiana) | 727.85 mi (1,171.35 km) |
| New Port Richey East to Everett (Massachusetts) | 1,174.59 mi (1,890.32 km) |
| New Port Richey East to Everett (Washington) | 2,501.13 mi (4,025.18 km) |
| New Port Richey East to Evergreen Park (Illinois) | 971.82 mi (1,563.99 km) |
| New Port Richey East to Ewa Beach (Hawaii) | 4,674.64 mi (7,523.10 km) |
| New Port Richey East to Ewa Gentry (Hawaii) | 4,675.32 mi (7,524.20 km) |
