| New Port Richey East to Effingham (Illinois) | 821.96 mi (1,322.81 km) |
| New Port Richey East to Eggertsville (New York) | 1,038.95 mi (1,672.03 km) |
| New Port Richey East to Egypt Lake-Leto (Florida) | 20.28 mi (32.63 km) |
| New Port Richey East to El Cajon (California) | 2,054.33 mi (3,306.12 km) |
| New Port Richey East to El Campo (Texas) | 824.82 mi (1,327.42 km) |
| New Port Richey East to El Centro (California) | 1,972.96 mi (3,175.18 km) |
| New Port Richey East to El Cerrito (California) | 2,368.53 mi (3,811.78 km) |
| New Port Richey East to El Dorado (Arkansas) | 683.58 mi (1,100.11 km) |
| New Port Richey East to El Dorado (Kansas) | 1,051.28 mi (1,691.87 km) |
| New Port Richey East to El Dorado Hills (California) | 2,305.82 mi (3,710.85 km) |
| New Port Richey East to El Mirage (Arizona) | 1,788.17 mi (2,877.78 km) |
| New Port Richey East to El Monte (California) | 2,116.53 mi (3,406.23 km) |
| New Port Richey East to El Paso (Texas) | 1,438.03 mi (2,314.29 km) |
| New Port Richey East to El Paso de Robles (California) | 2,268.53 mi (3,650.85 km) |
| New Port Richey East to El Reno (Oklahoma) | 1,025.71 mi (1,650.72 km) |
