| New Port Richey East to Eatontown (New Jersey) | 965.33 mi (1,553.55 km) |
| New Port Richey East to Eau Claire (Wisconsin) | 1,242.25 mi (1,999.20 km) |
| New Port Richey East to Echelon (New Jersey) | 912.96 mi (1,469.27 km) |
| New Port Richey East to Eden (North Carolina) | 594.86 mi (957.34 km) |
| New Port Richey East to Eden Prairie (Minnesota) | 1,289.84 mi (2,075.80 km) |
| New Port Richey East to Edgewater (Florida) | 116.75 mi (187.90 km) |
| New Port Richey East to Edgewater (New Jersey) | 998.59 mi (1,607.07 km) |
| New Port Richey East to Edgewood (Maryland) | 853.30 mi (1,373.25 km) |
| New Port Richey East to Edgewood (Washington) | 2,490.87 mi (4,008.67 km) |
| New Port Richey East to Edina (Minnesota) | 1,289.88 mi (2,075.87 km) |
| New Port Richey East to Edinburg (Texas) | 958.43 mi (1,542.45 km) |
| New Port Richey East to Edmond (Oklahoma) | 1,001.70 mi (1,612.07 km) |
| New Port Richey East to Edmonds (Washington) | 2,506.26 mi (4,033.44 km) |
| New Port Richey East to Edwards (Colorado) | 1,572.82 mi (2,531.20 km) |
| New Port Richey East to Edwardsville (Illinois) | 839.52 mi (1,351.08 km) |
