| New Port Richey to Superior (Colorado) | 1,510.20 mi (2,430.44 km) |
| New Port Richey to Superior (Wisconsin) | 1,371.77 mi (2,207.66 km) |
| New Port Richey to Surprise (Arizona) | 1,794.68 mi (2,888.25 km) |
| New Port Richey to Susanville (California) | 2,298.77 mi (3,699.51 km) |
| New Port Richey to Sussex (Wisconsin) | 1,073.39 mi (1,727.46 km) |
| New Port Richey to Suwanee (Georgia) | 408.89 mi (658.05 km) |
| New Port Richey to Swansea (Illinois) | 825.52 mi (1,328.54 km) |
| New Port Richey to Sweetwater (Florida) | 223.26 mi (359.30 km) |
| New Port Richey to Sweetwater (Texas) | 1,092.90 mi (1,758.85 km) |
| New Port Richey to Sycamore (Illinois) | 1,007.31 mi (1,621.11 km) |
| New Port Richey to Sylacauga (Alabama) | 400.42 mi (644.41 km) |
| New Port Richey to Sylvania (Ohio) | 931.89 mi (1,499.74 km) |
| New Port Richey to Syosset (New York) | 1,013.12 mi (1,630.46 km) |
| New Port Richey to Syracuse (New York) | 1,085.84 mi (1,747.49 km) |
| New Port Richey to Syracuse (Utah) | 1,876.39 mi (3,019.76 km) |
