| New Port Richey to Storm Lake (Iowa) | 1,214.73 mi (1,954.92 km) |
| New Port Richey to Storrs (Connecticut) | 1,106.44 mi (1,780.65 km) |
| New Port Richey to Stoughton (Wisconsin) | 1,077.06 mi (1,733.36 km) |
| New Port Richey to Stow (Ohio) | 896.29 mi (1,442.44 km) |
| New Port Richey to Streamwood (Illinois) | 999.89 mi (1,609.16 km) |
| New Port Richey to Streator (Illinois) | 954.47 mi (1,536.07 km) |
| New Port Richey to Streetsboro (Ohio) | 901.05 mi (1,450.10 km) |
| New Port Richey to Strongsville (Ohio) | 904.16 mi (1,455.10 km) |
| New Port Richey to Stuart (Florida) | 167.75 mi (269.97 km) |
| New Port Richey to Stuarts Draft (Virginia) | 707.80 mi (1,139.10 km) |
| New Port Richey to Sturgis (Michigan) | 948.62 mi (1,526.66 km) |
| New Port Richey to Suamico (Wisconsin) | 1,170.06 mi (1,883.04 km) |
| New Port Richey to Sudley (Virginia) | 787.58 mi (1,267.48 km) |
| New Port Richey to Suffern (New York) | 1,012.50 mi (1,629.46 km) |
| New Port Richey to Suffolk (Virginia) | 682.42 mi (1,098.25 km) |
