| New Port Richey to Stephenville (Texas) | 964.21 mi (1,551.75 km) |
| New Port Richey to Sterling (Colorado) | 1,440.47 mi (2,318.21 km) |
| New Port Richey to Sterling (Illinois) | 1,015.34 mi (1,634.03 km) |
| New Port Richey to Sterling (Virginia) | 803.29 mi (1,292.78 km) |
| New Port Richey to Sterling Heights (Michigan) | 990.55 mi (1,594.13 km) |
| New Port Richey to Steubenville (Ohio) | 845.49 mi (1,360.68 km) |
| New Port Richey to Stevens Point (Wisconsin) | 1,186.04 mi (1,908.75 km) |
| New Port Richey to Stevenson Ranch (California) | 2,147.92 mi (3,456.74 km) |
| New Port Richey to Stillwater (Minnesota) | 1,287.27 mi (2,071.67 km) |
| New Port Richey to Stillwater (Oklahoma) | 999.04 mi (1,607.81 km) |
| New Port Richey to Stockbridge (Georgia) | 375.56 mi (604.41 km) |
| New Port Richey to Stockton (California) | 2,314.16 mi (3,724.28 km) |
| New Port Richey to Stone Ridge (Virginia) | 795.25 mi (1,279.83 km) |
| New Port Richey to Stonecrest (Georgia) | 384.98 mi (619.57 km) |
| New Port Richey to Stony Brook (New York) | 1,029.31 mi (1,656.51 km) |
