| New Port Richey to St. Simons (Georgia) | 217.68 mi (350.31 km) |
| New Port Richey to Stafford (Texas) | 782.32 mi (1,259.03 km) |
| New Port Richey to Stallings (North Carolina) | 489.27 mi (787.40 km) |
| New Port Richey to Stamford (Connecticut) | 1,028.11 mi (1,654.58 km) |
| New Port Richey to Stanford (California) | 2,357.81 mi (3,794.53 km) |
| New Port Richey to Stanton (California) | 2,113.12 mi (3,400.74 km) |
| New Port Richey to Star (Idaho) | 2,148.11 mi (3,457.05 km) |
| New Port Richey to Starkville (Mississippi) | 510.90 mi (822.22 km) |
| New Port Richey to State College (Pennsylvania) | 909.39 mi (1,463.52 km) |
| New Port Richey to Staten Island (New York) | 981.15 mi (1,579.01 km) |
| New Port Richey to Statesboro (Georgia) | 294.94 mi (474.66 km) |
| New Port Richey to Statesville (North Carolina) | 531.86 mi (855.94 km) |
| New Port Richey to Staunton (Virginia) | 716.58 mi (1,153.22 km) |
| New Port Richey to Steamboat Springs (Colorado) | 1,605.74 mi (2,584.19 km) |
| New Port Richey to Steiner Ranch (Texas) | 925.45 mi (1,489.36 km) |
