| New Port Richey to St. George (Utah) | 1,885.90 mi (3,035.06 km) |
| New Port Richey to St. Helens (Oregon) | 2,488.04 mi (4,004.11 km) |
| New Port Richey to St. James (New York) | 1,026.88 mi (1,652.61 km) |
| New Port Richey to St. John (Indiana) | 950.34 mi (1,529.42 km) |
| New Port Richey to St. Joseph (Missouri) | 1,053.11 mi (1,694.82 km) |
| New Port Richey to St. Louis (Missouri) | 838.07 mi (1,348.75 km) |
| New Port Richey to St. Louis Park (Minnesota) | 1,293.69 mi (2,081.99 km) |
| New Port Richey to St. Marys (Georgia) | 186.58 mi (300.27 km) |
| New Port Richey to St. Marys (Pennsylvania) | 942.74 mi (1,517.20 km) |
| New Port Richey to St. Matthews (Kentucky) | 711.33 mi (1,144.78 km) |
| New Port Richey to St. Michael (Minnesota) | 1,316.84 mi (2,119.25 km) |
| New Port Richey to St. Paul (Minnesota) | 1,287.22 mi (2,071.58 km) |
| New Port Richey to St. Peter (Minnesota) | 1,272.81 mi (2,048.38 km) |
| New Port Richey to St. Peters (Missouri) | 857.32 mi (1,379.72 km) |
| New Port Richey to St. Petersburg (Florida) | 31.51 mi (50.70 km) |
