| New Port Richey to Security-Widefield (Colorado) | 1,454.78 mi (2,341.24 km) |
| New Port Richey to Sedalia (Missouri) | 941.77 mi (1,515.63 km) |
| New Port Richey to Sedro-Woolley (Washington) | 2,516.09 mi (4,049.25 km) |
| New Port Richey to Seguin (Texas) | 926.30 mi (1,490.74 km) |
| New Port Richey to Selden (New York) | 1,029.78 mi (1,657.26 km) |
| New Port Richey to Selma (Alabama) | 386.27 mi (621.64 km) |
| New Port Richey to Selma (California) | 2,213.10 mi (3,561.64 km) |
| New Port Richey to Selma (Texas) | 947.05 mi (1,524.13 km) |
| New Port Richey to Seminole (Florida) | 28.16 mi (45.32 km) |
| New Port Richey to Seven Hills (Ohio) | 909.34 mi (1,463.45 km) |
| New Port Richey to Seven Oaks (South Carolina) | 411.43 mi (662.13 km) |
| New Port Richey to Severn (Maryland) | 827.62 mi (1,331.93 km) |
| New Port Richey to Severna Park (Maryland) | 827.69 mi (1,332.04 km) |
| New Port Richey to Sevierville (Tennessee) | 530.24 mi (853.34 km) |
| New Port Richey to Seymour (Indiana) | 761.44 mi (1,225.41 km) |
