| New Port Richey to Scottsboro (Alabama) | 483.58 mi (778.24 km) |
| New Port Richey to Scottsdale (Arizona) | 1,761.08 mi (2,834.19 km) |
| New Port Richey to Scranton (Pennsylvania) | 992.30 mi (1,596.95 km) |
| New Port Richey to Seabrook (Maryland) | 814.33 mi (1,310.53 km) |
| New Port Richey to Seabrook (Texas) | 749.60 mi (1,206.36 km) |
| New Port Richey to Seaford (New York) | 1,004.94 mi (1,617.30 km) |
| New Port Richey to Seagoville (Texas) | 877.27 mi (1,411.83 km) |
| New Port Richey to Seal Beach (California) | 2,117.56 mi (3,407.88 km) |
| New Port Richey to Searcy (Arkansas) | 716.55 mi (1,153.18 km) |
| New Port Richey to Seaside (California) | 2,335.43 mi (3,758.50 km) |
| New Port Richey to SeaTac (Washington) | 2,495.60 mi (4,016.29 km) |
| New Port Richey to Seattle (Washington) | 2,500.50 mi (4,024.16 km) |
| New Port Richey to Sebastian (Florida) | 140.06 mi (225.41 km) |
| New Port Richey to Sebring (Florida) | 93.76 mi (150.89 km) |
| New Port Richey to Secaucus (New Jersey) | 995.03 mi (1,601.35 km) |
