| New Port Richey to San Luis Obispo (California) | 2,267.46 mi (3,649.13 km) |
| New Port Richey to San Marcos (California) | 2,065.56 mi (3,324.20 km) |
| New Port Richey to San Marcos (Texas) | 925.28 mi (1,489.10 km) |
| New Port Richey to San Marino (California) | 2,120.37 mi (3,412.41 km) |
| New Port Richey to San Mateo (California) | 2,366.32 mi (3,808.23 km) |
| New Port Richey to San Pablo (California) | 2,370.07 mi (3,814.26 km) |
| New Port Richey to San Rafael (California) | 2,379.96 mi (3,830.18 km) |
| New Port Richey to San Ramon (California) | 2,346.90 mi (3,776.97 km) |
| New Port Richey to San Tan Valley (Arizona) | 1,741.27 mi (2,802.31 km) |
| New Port Richey to Sand Springs (Oklahoma) | 953.46 mi (1,534.45 km) |
| New Port Richey to Sandusky (Ohio) | 912.03 mi (1,467.77 km) |
| New Port Richey to Sandy (Oregon) | 2,454.27 mi (3,949.77 km) |
| New Port Richey to Sandy (Utah) | 1,854.21 mi (2,984.06 km) |
| New Port Richey to Sandy Springs (Georgia) | 405.09 mi (651.94 km) |
| New Port Richey to Sanford (Florida) | 95.19 mi (153.19 km) |
