| New Port Richey to Oswego (Illinois) | 980.81 mi (1,578.46 km) |
| New Port Richey to Oswego (New York) | 1,105.89 mi (1,779.76 km) |
| New Port Richey to Otsego (Minnesota) | 1,318.89 mi (2,122.54 km) |
| New Port Richey to Ottawa (Illinois) | 969.09 mi (1,559.61 km) |
| New Port Richey to Ottawa (Kansas) | 1,015.49 mi (1,634.28 km) |
| New Port Richey to Ottumwa (Iowa) | 1,039.09 mi (1,672.26 km) |
| New Port Richey to Overland (Missouri) | 845.26 mi (1,360.31 km) |
| New Port Richey to Overland Park (Kansas) | 1,005.82 mi (1,618.70 km) |
| New Port Richey to Overlea (Maryland) | 846.02 mi (1,361.53 km) |
| New Port Richey to Oviedo (Florida) | 97.18 mi (156.39 km) |
| New Port Richey to Owasso (Oklahoma) | 944.89 mi (1,520.66 km) |
| New Port Richey to Owatonna (Minnesota) | 1,239.48 mi (1,994.76 km) |
| New Port Richey to Owensboro (Kentucky) | 704.61 mi (1,133.96 km) |
| New Port Richey to Owings Mills (Maryland) | 842.53 mi (1,355.91 km) |
| New Port Richey to Owosso (Michigan) | 1,022.28 mi (1,645.20 km) |
