| New Port Richey to Orangevale (California) | 2,314.30 mi (3,724.50 km) |
| New Port Richey to Orchards (Washington) | 2,471.70 mi (3,977.82 km) |
| New Port Richey to Orcutt (California) | 2,252.88 mi (3,625.66 km) |
| New Port Richey to Oregon (Ohio) | 927.11 mi (1,492.04 km) |
| New Port Richey to Oregon (Wisconsin) | 1,080.33 mi (1,738.63 km) |
| New Port Richey to Oregon City (Oregon) | 2,468.39 mi (3,972.50 km) |
| New Port Richey to Orem (Utah) | 1,840.81 mi (2,962.51 km) |
| New Port Richey to Orinda (California) | 2,360.73 mi (3,799.23 km) |
| New Port Richey to Orland Park (Illinois) | 967.55 mi (1,557.12 km) |
| New Port Richey to Orlando (Florida) | 85.40 mi (137.44 km) |
| New Port Richey to Ormond Beach (Florida) | 121.87 mi (196.14 km) |
| New Port Richey to Oro Valley (Arizona) | 1,704.63 mi (2,743.33 km) |
| New Port Richey to Oroville (California) | 2,339.25 mi (3,764.65 km) |
| New Port Richey to Oshkosh (Wisconsin) | 1,136.97 mi (1,829.78 km) |
| New Port Richey to Oskaloosa (Iowa) | 1,061.15 mi (1,707.75 km) |
