| New Port Richey to Odessa (Texas) | 1,198.45 mi (1,928.71 km) |
| New Port Richey to Ogden (Utah) | 1,874.61 mi (3,016.89 km) |
| New Port Richey to Oildale (California) | 2,175.63 mi (3,501.33 km) |
| New Port Richey to Ojus (Florida) | 223.07 mi (359.00 km) |
| New Port Richey to Okemos (Michigan) | 1,003.50 mi (1,614.98 km) |
| New Port Richey to Oklahoma City (Oklahoma) | 999.80 mi (1,609.03 km) |
| New Port Richey to Okmulgee (Oklahoma) | 929.41 mi (1,495.73 km) |
| New Port Richey to Olathe (Kansas) | 1,010.86 mi (1,626.81 km) |
| New Port Richey to Old Jamestown (Missouri) | 851.02 mi (1,369.58 km) |
| New Port Richey to Oldsmar (Florida) | 13.86 mi (22.30 km) |
| New Port Richey to Olean (New York) | 985.71 mi (1,586.35 km) |
| New Port Richey to Olive Branch (Mississippi) | 625.10 mi (1,006.00 km) |
| New Port Richey to Olivehurst (California) | 2,335.33 mi (3,758.35 km) |
| New Port Richey to Olney (Maryland) | 819.58 mi (1,318.98 km) |
| New Port Richey to Olympia (Washington) | 2,514.13 mi (4,046.10 km) |
