| New Port Richey to Lovington (New Mexico) | 1,265.34 mi (2,036.36 km) |
| New Port Richey to Lowell (Indiana) | 939.59 mi (1,512.13 km) |
| New Port Richey to Lowell (Massachusetts) | 1,180.82 mi (1,900.35 km) |
| New Port Richey to Lower Burrell (Pennsylvania) | 869.13 mi (1,398.72 km) |
| New Port Richey to Lowes Island (Virginia) | 807.09 mi (1,298.88 km) |
| New Port Richey to Lubbock (Texas) | 1,192.29 mi (1,918.81 km) |
| New Port Richey to Lufkin (Texas) | 750.44 mi (1,207.72 km) |
| New Port Richey to Luling (Louisiana) | 474.92 mi (764.31 km) |
| New Port Richey to Lumberton (North Carolina) | 491.95 mi (791.71 km) |
| New Port Richey to Lumberton (Texas) | 706.09 mi (1,136.34 km) |
| New Port Richey to Lutz (Florida) | 18.05 mi (29.05 km) |
| New Port Richey to Lynbrook (New York) | 999.05 mi (1,607.81 km) |
| New Port Richey to Lynchburg (Virginia) | 664.60 mi (1,069.58 km) |
| New Port Richey to Lynden (Washington) | 2,535.72 mi (4,080.85 km) |
| New Port Richey to Lyndhurst (Ohio) | 919.49 mi (1,479.78 km) |
