| New Port Richey to Indianapolis (Indiana) | 820.32 mi (1,320.18 km) |
| New Port Richey to Indianola (Iowa) | 1,093.44 mi (1,759.71 km) |
| New Port Richey to Indio (California) | 2,012.02 mi (3,238.04 km) |
| New Port Richey to Inglewood (California) | 2,133.40 mi (3,433.37 km) |
| New Port Richey to Inkster (Michigan) | 971.11 mi (1,562.85 km) |
| New Port Richey to Inver Grove Heights (Minnesota) | 1,278.76 mi (2,057.97 km) |
| New Port Richey to Inwood (New York) | 994.76 mi (1,600.91 km) |
| New Port Richey to Iona (Florida) | 128.29 mi (206.46 km) |
| New Port Richey to Ionia (Michigan) | 1,026.22 mi (1,651.55 km) |
| New Port Richey to Iowa City (Iowa) | 1,050.95 mi (1,691.34 km) |
| New Port Richey to Irmo (South Carolina) | 414.40 mi (666.91 km) |
| New Port Richey to Irondale (Alabama) | 434.21 mi (698.79 km) |
| New Port Richey to Ironton (Ohio) | 710.66 mi (1,143.70 km) |
| New Port Richey to Irvine (California) | 2,100.39 mi (3,380.26 km) |
| New Port Richey to Irving (Texas) | 904.98 mi (1,456.43 km) |
