| Natchez to Oswego (Illinois) | 720.57 mi (1,159.65 km) |
| Natchez to Oswego (New York) | 1,155.32 mi (1,859.31 km) |
| Natchez to Otsego (Minnesota) | 955.69 mi (1,538.04 km) |
| Natchez to Ottawa (Illinois) | 692.61 mi (1,114.65 km) |
| Natchez to Ottawa (Kansas) | 534.39 mi (860.02 km) |
| Natchez to Ottumwa (Iowa) | 657.22 mi (1,057.69 km) |
| Natchez to Overland (Missouri) | 497.54 mi (800.72 km) |
| Natchez to Overland Park (Kansas) | 540.38 mi (869.66 km) |
| Natchez to Overlea (Maryland) | 994.11 mi (1,599.86 km) |
| Natchez to Oviedo (Florida) | 641.14 mi (1,031.81 km) |
| Natchez to Owasso (Oklahoma) | 415.07 mi (667.99 km) |
| Natchez to Owatonna (Minnesota) | 872.71 mi (1,404.49 km) |
| Natchez to Owensboro (Kentucky) | 493.02 mi (793.44 km) |
| Natchez to Owings Mills (Maryland) | 982.85 mi (1,581.75 km) |
| Natchez to Owosso (Michigan) | 884.16 mi (1,422.92 km) |
