| Nacogdoches to Superior (Colorado) | 821.87 mi (1,322.67 km) |
| Nacogdoches to Superior (Wisconsin) | 1,050.88 mi (1,691.23 km) |
| Nacogdoches to Surprise (Arizona) | 1,043.95 mi (1,680.08 km) |
| Nacogdoches to Susanville (California) | 1,565.83 mi (2,519.95 km) |
| Nacogdoches to Sussex (Wisconsin) | 870.13 mi (1,400.34 km) |
| Nacogdoches to Suwanee (Georgia) | 636.79 mi (1,024.82 km) |
| Nacogdoches to Swansea (Illinois) | 546.95 mi (880.23 km) |
| Nacogdoches to Sweetwater (Florida) | 953.47 mi (1,534.47 km) |
| Nacogdoches to Sweetwater (Texas) | 342.24 mi (550.78 km) |
| Nacogdoches to Sycamore (Illinois) | 789.21 mi (1,270.11 km) |
| Nacogdoches to Sylacauga (Alabama) | 501.25 mi (806.68 km) |
| Nacogdoches to Sylvania (Ohio) | 922.83 mi (1,485.15 km) |
| Nacogdoches to Syosset (New York) | 1,334.57 mi (2,147.78 km) |
| Nacogdoches to Syracuse (New York) | 1,282.49 mi (2,063.96 km) |
| Nacogdoches to Syracuse (Utah) | 1,166.01 mi (1,876.52 km) |
