| Nacogdoches to Storm Lake (Iowa) | 762.66 mi (1,227.38 km) |
| Nacogdoches to Storrs (Connecticut) | 1,420.51 mi (2,286.08 km) |
| Nacogdoches to Stoughton (Wisconsin) | 836.08 mi (1,345.53 km) |
| Nacogdoches to Stow (Ohio) | 986.35 mi (1,587.38 km) |
| Nacogdoches to Streamwood (Illinois) | 802.72 mi (1,291.85 km) |
| Nacogdoches to Streator (Illinois) | 732.22 mi (1,178.39 km) |
| Nacogdoches to Streetsboro (Ohio) | 992.67 mi (1,597.55 km) |
| Nacogdoches to Strongsville (Ohio) | 976.10 mi (1,570.87 km) |
| Nacogdoches to Stuart (Florida) | 918.50 mi (1,478.18 km) |
| Nacogdoches to Stuarts Draft (Virginia) | 988.47 mi (1,590.79 km) |
| Nacogdoches to Sturgis (Michigan) | 868.84 mi (1,398.27 km) |
| Nacogdoches to Suamico (Wisconsin) | 967.46 mi (1,556.98 km) |
| Nacogdoches to Sudley (Virginia) | 1,085.63 mi (1,747.16 km) |
| Nacogdoches to Suffern (New York) | 1,311.64 mi (2,110.88 km) |
| Nacogdoches to Suffolk (Virginia) | 1,086.10 mi (1,747.90 km) |
