| Nacogdoches to Scottsboro (Alabama) | 539.82 mi (868.75 km) |
| Nacogdoches to Scottsdale (Arizona) | 1,010.31 mi (1,625.94 km) |
| Nacogdoches to Scranton (Pennsylvania) | 1,248.52 mi (2,009.29 km) |
| Nacogdoches to Seabrook (Maryland) | 1,122.82 mi (1,807.01 km) |
| Nacogdoches to Seabrook (Texas) | 142.55 mi (229.41 km) |
| Nacogdoches to Seaford (New York) | 1,331.30 mi (2,142.51 km) |
| Nacogdoches to Seagoville (Texas) | 132.00 mi (212.43 km) |
| Nacogdoches to Seal Beach (California) | 1,366.92 mi (2,199.85 km) |
| Nacogdoches to Searcy (Arkansas) | 301.88 mi (485.83 km) |
| Nacogdoches to Seaside (California) | 1,586.38 mi (2,553.02 km) |
| Nacogdoches to SeaTac (Washington) | 1,818.67 mi (2,926.87 km) |
| Nacogdoches to Seattle (Washington) | 1,825.31 mi (2,937.55 km) |
| Nacogdoches to Sebastian (Florida) | 889.94 mi (1,432.22 km) |
| Nacogdoches to Sebring (Florida) | 842.61 mi (1,356.05 km) |
| Nacogdoches to Secaucus (New Jersey) | 1,306.34 mi (2,102.34 km) |
