| Nacogdoches to Santa Rosa (California) | 1,648.60 mi (2,653.17 km) |
| Nacogdoches to Santaquin (Utah) | 1,117.93 mi (1,799.14 km) |
| Nacogdoches to Santee (California) | 1,305.58 mi (2,101.14 km) |
| Nacogdoches to Sapulpa (Oklahoma) | 314.86 mi (506.72 km) |
| Nacogdoches to Saraland (Alabama) | 390.66 mi (628.70 km) |
| Nacogdoches to Sarasota (Florida) | 785.38 mi (1,263.95 km) |
| Nacogdoches to Sarasota Springs (Florida) | 790.08 mi (1,271.50 km) |
| Nacogdoches to Saratoga (California) | 1,601.83 mi (2,577.89 km) |
| Nacogdoches to Saratoga Springs (New York) | 1,387.03 mi (2,232.20 km) |
| Nacogdoches to Saratoga Springs (Utah) | 1,135.10 mi (1,826.77 km) |
| Nacogdoches to Sartell (Minnesota) | 967.96 mi (1,557.78 km) |
| Nacogdoches to Satellite Beach (Florida) | 873.72 mi (1,406.11 km) |
| Nacogdoches to Sauk Rapids (Minnesota) | 966.62 mi (1,555.62 km) |
| Nacogdoches to Sault Ste. Marie (Michigan) | 1,163.72 mi (1,872.82 km) |
| Nacogdoches to Savage (Minnesota) | 910.63 mi (1,465.51 km) |
