| Mytilini to Santander | 1,595.42 mi (2,567.59 km) |
| Mytilini to Santany | 1,250.19 mi (2,011.99 km) |
| Mytilini to Santiago de Compostela | 1,835.33 mi (2,953.68 km) |
| Mytilini to Santiago del Teide | 2,575.52 mi (4,144.90 km) |
| Mytilini to Santiponce | 1,762.35 mi (2,836.23 km) |
| Mytilini to Santomera | 1,486.69 mi (2,392.59 km) |
| Mytilini to Santona | 1,577.98 mi (2,539.52 km) |
| Mytilini to Santurce-Antiguo | 1,556.50 mi (2,504.95 km) |
| Mytilini to Sarria | 1,778.72 mi (2,862.57 km) |
| Mytilini to Sauzal | 2,549.21 mi (4,102.56 km) |
| Mytilini to Sedavi | 1,435.68 mi (2,310.50 km) |
| Mytilini to Segorbe | 1,437.52 mi (2,313.47 km) |
| Mytilini to Segovia | 1,619.34 mi (2,606.08 km) |
| Mytilini to Senmanat | 1,292.71 mi (2,080.41 km) |
| Mytilini to Sesena | 1,604.01 mi (2,581.40 km) |
