| Muscle Shoals to Superior (Colorado) | 1,025.17 mi (1,649.86 km) |
| Muscle Shoals to Superior (Wisconsin) | 857.57 mi (1,380.13 km) |
| Muscle Shoals to Surprise (Arizona) | 1,416.29 mi (2,279.31 km) |
| Muscle Shoals to Susanville (California) | 1,836.63 mi (2,955.76 km) |
| Muscle Shoals to Sussex (Wisconsin) | 580.65 mi (934.46 km) |
| Muscle Shoals to Suwanee (Georgia) | 208.83 mi (336.08 km) |
| Muscle Shoals to Swansea (Illinois) | 293.57 mi (472.45 km) |
| Muscle Shoals to Sweetwater (Florida) | 755.28 mi (1,215.51 km) |
| Muscle Shoals to Sweetwater (Texas) | 751.17 mi (1,208.89 km) |
| Muscle Shoals to Sycamore (Illinois) | 504.29 mi (811.58 km) |
| Muscle Shoals to Sylacauga (Alabama) | 133.76 mi (215.27 km) |
| Muscle Shoals to Sylvania (Ohio) | 526.24 mi (846.90 km) |
| Muscle Shoals to Syosset (New York) | 876.90 mi (1,411.23 km) |
| Muscle Shoals to Syracuse (New York) | 841.45 mi (1,354.19 km) |
| Muscle Shoals to Syracuse (Utah) | 1,396.72 mi (2,247.81 km) |
