| Muscle Shoals to Storm Lake (Iowa) | 680.70 mi (1,095.48 km) |
| Muscle Shoals to Storrs (Connecticut) | 964.54 mi (1,552.28 km) |
| Muscle Shoals to Stoughton (Wisconsin) | 571.61 mi (919.92 km) |
| Muscle Shoals to Stow (Ohio) | 557.92 mi (897.88 km) |
| Muscle Shoals to Streamwood (Illinois) | 503.70 mi (810.62 km) |
| Muscle Shoals to Streator (Illinois) | 445.68 mi (717.25 km) |
| Muscle Shoals to Streetsboro (Ohio) | 564.21 mi (908.01 km) |
| Muscle Shoals to Strongsville (Ohio) | 552.67 mi (889.44 km) |
| Muscle Shoals to Stuart (Florida) | 680.41 mi (1,095.01 km) |
| Muscle Shoals to Stuarts Draft (Virginia) | 528.87 mi (851.13 km) |
| Muscle Shoals to Sturgis (Michigan) | 502.06 mi (807.99 km) |
| Muscle Shoals to Suamico (Wisconsin) | 683.87 mi (1,100.58 km) |
| Muscle Shoals to Sudley (Virginia) | 626.37 mi (1,008.05 km) |
| Muscle Shoals to Suffern (New York) | 855.52 mi (1,376.82 km) |
| Muscle Shoals to Suffolk (Virginia) | 630.93 mi (1,015.39 km) |
