| Muscle Shoals to Smyrna (Delaware) | 733.34 mi (1,180.19 km) |
| Muscle Shoals to Smyrna (Georgia) | 188.02 mi (302.59 km) |
| Muscle Shoals to Smyrna (Tennessee) | 105.20 mi (169.30 km) |
| Muscle Shoals to Snellville (Georgia) | 216.08 mi (347.75 km) |
| Muscle Shoals to Snoqualmie (Washington) | 1,965.78 mi (3,163.62 km) |
| Muscle Shoals to Snyder (Texas) | 775.13 mi (1,247.46 km) |
| Muscle Shoals to Socastee (South Carolina) | 498.04 mi (801.52 km) |
| Muscle Shoals to Socorro (Texas) | 1,096.42 mi (1,764.52 km) |
| Muscle Shoals to Soddy-Daisy (Tennessee) | 143.70 mi (231.27 km) |
| Muscle Shoals to Solana Beach (California) | 1,697.62 mi (2,732.06 km) |
| Muscle Shoals to Soledad (California) | 1,887.91 mi (3,038.30 km) |
| Muscle Shoals to Solon (Ohio) | 569.06 mi (915.81 km) |
| Muscle Shoals to Somers Point (New Jersey) | 784.01 mi (1,261.75 km) |
| Muscle Shoals to Somerset (Kentucky) | 234.00 mi (376.59 km) |
| Muscle Shoals to Somerset (New Jersey) | 820.44 mi (1,320.38 km) |
