| Muscle Shoals to Silver Firs (Washington) | 1,985.38 mi (3,195.16 km) |
| Muscle Shoals to Silver Spring (Maryland) | 655.73 mi (1,055.30 km) |
| Muscle Shoals to Silver Springs Shores (Florida) | 509.63 mi (820.17 km) |
| Muscle Shoals to Silverdale (Washington) | 2,006.12 mi (3,228.53 km) |
| Muscle Shoals to Silverton (Oregon) | 1,975.25 mi (3,178.85 km) |
| Muscle Shoals to Simi Valley (California) | 1,764.80 mi (2,840.16 km) |
| Muscle Shoals to Simpsonville (South Carolina) | 305.29 mi (491.32 km) |
| Muscle Shoals to Sioux City (Iowa) | 713.57 mi (1,148.38 km) |
| Muscle Shoals to Sioux Falls (South Dakota) | 778.09 mi (1,252.22 km) |
| Muscle Shoals to Skokie (Illinois) | 503.92 mi (810.97 km) |
| Muscle Shoals to Sleepy Hollow (New York) | 867.50 mi (1,396.11 km) |
| Muscle Shoals to Slidell (Louisiana) | 332.23 mi (534.67 km) |
| Muscle Shoals to Smithfield (North Carolina) | 527.17 mi (848.39 km) |
| Muscle Shoals to Smithfield (Utah) | 1,394.68 mi (2,244.52 km) |
| Muscle Shoals to Smithville (Missouri) | 499.29 mi (803.53 km) |
