| Muscle Shoals to Santa Rosa (California) | 1,950.48 mi (3,139.00 km) |
| Muscle Shoals to Santaquin (Utah) | 1,370.39 mi (2,205.43 km) |
| Muscle Shoals to Santee (California) | 1,684.28 mi (2,710.59 km) |
| Muscle Shoals to Sapulpa (Oklahoma) | 484.73 mi (780.10 km) |
| Muscle Shoals to Saraland (Alabama) | 270.50 mi (435.32 km) |
| Muscle Shoals to Sarasota (Florida) | 593.54 mi (955.21 km) |
| Muscle Shoals to Sarasota Springs (Florida) | 597.41 mi (961.44 km) |
| Muscle Shoals to Saratoga (California) | 1,919.63 mi (3,089.35 km) |
| Muscle Shoals to Saratoga Springs (New York) | 939.11 mi (1,511.35 km) |
| Muscle Shoals to Saratoga Springs (Utah) | 1,380.35 mi (2,221.47 km) |
| Muscle Shoals to Sartell (Minnesota) | 827.24 mi (1,331.32 km) |
| Muscle Shoals to Satellite Beach (Florida) | 614.06 mi (988.24 km) |
| Muscle Shoals to Sauk Rapids (Minnesota) | 824.51 mi (1,326.91 km) |
| Muscle Shoals to Sault Ste. Marie (Michigan) | 828.70 mi (1,333.67 km) |
| Muscle Shoals to Savage (Minnesota) | 755.20 mi (1,215.38 km) |
