| Muscle Shoals to Oswego (Illinois) | 481.03 mi (774.15 km) |
| Muscle Shoals to Oswego (New York) | 846.15 mi (1,361.74 km) |
| Muscle Shoals to Otsego (Minnesota) | 792.50 mi (1,275.40 km) |
| Muscle Shoals to Ottawa (Illinois) | 461.43 mi (742.60 km) |
| Muscle Shoals to Ottawa (Kansas) | 499.48 mi (803.84 km) |
| Muscle Shoals to Ottumwa (Iowa) | 505.88 mi (814.14 km) |
| Muscle Shoals to Overland (Missouri) | 312.29 mi (502.58 km) |
| Muscle Shoals to Overland Park (Kansas) | 483.65 mi (778.36 km) |
| Muscle Shoals to Overlea (Maryland) | 690.45 mi (1,111.17 km) |
| Muscle Shoals to Oviedo (Florida) | 565.76 mi (910.50 km) |
| Muscle Shoals to Owasso (Oklahoma) | 473.01 mi (761.23 km) |
| Muscle Shoals to Owatonna (Minnesota) | 711.19 mi (1,144.55 km) |
| Muscle Shoals to Owensboro (Kentucky) | 210.25 mi (338.37 km) |
| Muscle Shoals to Owings Mills (Maryland) | 678.51 mi (1,091.95 km) |
| Muscle Shoals to Owosso (Michigan) | 599.61 mi (964.98 km) |
