| Muscle Shoals to Orangevale (California) | 1,869.50 mi (3,008.67 km) |
| Muscle Shoals to Orchards (Washington) | 1,971.01 mi (3,172.04 km) |
| Muscle Shoals to Orcutt (California) | 1,851.69 mi (2,980.00 km) |
| Muscle Shoals to Oregon (Ohio) | 528.93 mi (851.23 km) |
| Muscle Shoals to Oregon (Wisconsin) | 573.12 mi (922.36 km) |
| Muscle Shoals to Oregon City (Oregon) | 1,969.87 mi (3,170.21 km) |
| Muscle Shoals to Orem (Utah) | 1,368.62 mi (2,202.58 km) |
| Muscle Shoals to Orinda (California) | 1,924.47 mi (3,097.13 km) |
| Muscle Shoals to Orland Park (Illinois) | 474.44 mi (763.53 km) |
| Muscle Shoals to Orlando (Florida) | 569.56 mi (916.63 km) |
| Muscle Shoals to Ormond Beach (Florida) | 536.38 mi (863.21 km) |
| Muscle Shoals to Oro Valley (Arizona) | 1,350.10 mi (2,172.78 km) |
| Muscle Shoals to Oroville (California) | 1,886.44 mi (3,035.94 km) |
| Muscle Shoals to Oshkosh (Wisconsin) | 643.05 mi (1,034.89 km) |
| Muscle Shoals to Oskaloosa (Iowa) | 527.97 mi (849.69 km) |
