| Muscle Shoals to Odessa (Texas) | 871.24 mi (1,402.13 km) |
| Muscle Shoals to Ogden (Utah) | 1,393.33 mi (2,242.35 km) |
| Muscle Shoals to Oildale (California) | 1,768.22 mi (2,845.68 km) |
| Muscle Shoals to Ojus (Florida) | 752.53 mi (1,211.08 km) |
| Muscle Shoals to Okemos (Michigan) | 576.77 mi (928.23 km) |
| Muscle Shoals to Oklahoma City (Oklahoma) | 560.43 mi (901.92 km) |
| Muscle Shoals to Okmulgee (Oklahoma) | 476.49 mi (766.83 km) |
| Muscle Shoals to Olathe (Kansas) | 489.45 mi (787.69 km) |
| Muscle Shoals to Old Jamestown (Missouri) | 318.72 mi (512.93 km) |
| Muscle Shoals to Oldsmar (Florida) | 547.11 mi (880.49 km) |
| Muscle Shoals to Olean (New York) | 710.01 mi (1,142.65 km) |
| Muscle Shoals to Olive Branch (Mississippi) | 126.35 mi (203.34 km) |
| Muscle Shoals to Olivehurst (California) | 1,886.67 mi (3,036.30 km) |
| Muscle Shoals to Olney (Maryland) | 657.25 mi (1,057.74 km) |
| Muscle Shoals to Olympia (Washington) | 2,006.23 mi (3,228.72 km) |
