| Muscle Shoals to Elyria (Ohio) | 547.87 mi (881.71 km) |
| Muscle Shoals to Emeryville (California) | 1,930.90 mi (3,107.48 km) |
| Muscle Shoals to Emmaus (Pennsylvania) | 774.22 mi (1,245.99 km) |
| Muscle Shoals to Emporia (Kansas) | 537.71 mi (865.36 km) |
| Muscle Shoals to Encinitas (California) | 1,697.02 mi (2,731.09 km) |
| Muscle Shoals to Endicott (New York) | 805.27 mi (1,295.95 km) |
| Muscle Shoals to Endwell (New York) | 807.84 mi (1,300.09 km) |
| Muscle Shoals to Englewood (Colorado) | 1,011.74 mi (1,628.23 km) |
| Muscle Shoals to Englewood (Florida) | 621.40 mi (1,000.05 km) |
| Muscle Shoals to Englewood (New Jersey) | 856.70 mi (1,378.72 km) |
| Muscle Shoals to Englewood (Ohio) | 398.21 mi (640.86 km) |
| Muscle Shoals to Enid (Oklahoma) | 586.28 mi (943.53 km) |
| Muscle Shoals to Ennis (Texas) | 544.37 mi (876.09 km) |
| Muscle Shoals to Ensley (Florida) | 292.14 mi (470.16 km) |
| Muscle Shoals to Enterprise (Alabama) | 257.71 mi (414.75 km) |
