| Murrysville to Southern Pines (North Carolina) | 363.20 mi (584.51 km) |
| Murrysville to Southfield (Michigan) | 233.49 mi (375.77 km) |
| Murrysville to Southgate (Michigan) | 220.67 mi (355.13 km) |
| Murrysville to Southlake (Texas) | 1,095.90 mi (1,763.68 km) |
| Murrysville to Spanaway (Washington) | 2,154.52 mi (3,467.37 km) |
| Murrysville to Spanish Fork (Utah) | 1,676.87 mi (2,698.65 km) |
| Murrysville to Spanish Lake (Missouri) | 572.82 mi (921.86 km) |
| Murrysville to Spanish Springs (Nevada) | 2,098.67 mi (3,377.48 km) |
| Murrysville to Sparks (Nevada) | 2,102.53 mi (3,383.70 km) |
| Murrysville to Spartanburg (South Carolina) | 399.81 mi (643.43 km) |
| Murrysville to Spearfish (South Dakota) | 1,257.72 mi (2,024.10 km) |
| Murrysville to Speedway (Indiana) | 351.14 mi (565.11 km) |
| Murrysville to Spencer (Iowa) | 818.53 mi (1,317.30 km) |
| Murrysville to Spokane (Washington) | 1,920.25 mi (3,090.35 km) |
| Murrysville to Spokane Valley (Washington) | 1,911.02 mi (3,075.48 km) |
